Werewolf and Ambros Therapeutics announce merger

21 August 2026

US cancer care biotech Werewolf Therapeutics (Nasdaq: HOWL) and Ambros Therapeutics today announced that they entered into a definitive merger agreement to combine the companies in an all-stock transaction. Werewolf’s shares leapt 128% to $0.99 on the news.

The combined company will focus on advancing Ambros Therapeutics’ neridronate development program in Complex Regional Pain Syndrome Type 1 (CRPS-1, formerly known as Reflex Sympathetic Dystrophy). Upon completion of the merger, the combined company will operate as Ambros Therapeutics, headquartered in San Diego, California, and is expected to trade under the Nasdaq ticker symbol “AMBX”.

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