XOMA to buy struggling Generation Bio

16 December 2025

USA-based XOMA Royalty Corporation (Nasdaq: XOMA) is to acquire Generation Bio (Nasdaq: GBIO) for around $4.29 per share.

Generation Bio is a US biotech that was historically working to change what is possible for people living with T cell-driven autoimmune diseases.  Its approach used cell-targeted lipid nanoparticles to selectively deliver small interfering RNA to T cells. 

The company had raised $200 million in an initial public offering in 2020, attracting investment with the promise of developing a new type of gene therapy technology that relied on lipid nanoparticles, rather than engineered viruses, to deliver their genetic cargo.

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