Affinia Therapeutics closes $40M Series C financing

7 October 2025

Massachusetts, USA-based Affinia Therapeutics, an innovative gene therapy company with a pipeline of first-in-class and/or best-in-class adeno-associated virus (AAV) gene therapies for devastating cardiovascular and neurological diseases, today announced it has closed a $40 million Series C financing.

The financing was led by New Enterprise Associates (NEA) with participation from new investor, Eli Lilly (NYSE: LLY) and existing investors Alexandria Venture Investments, LLC, Atlas Venture, Avidity Partners, F-Prime, GV (formerly Google Ventures), Mass General Brigham Ventures, and Perceptive Advisors.

The proceeds from the financing will fund development of Affinia’s lead program, AFTX-201, a potential first-in-class and best-in-class investigational genetic medicine for the treatment of BAG3 dilated cardiomyopathy (DCM).

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