Allergan announces another potential acquisition

10 January 2017

Dublin, Ireland-headquartered Allergan (NYSE: AGN) has purchased an option to acquire Lysosomal Therapeutics (LTI), a privately owned small molecule specialist based in the USA, which is focused on developing novel therapies against neurodegenerative diseases.

Its lead investigational compound LTI-291 targets Parkinson’s disease and related disorders. Under the terms of the agreement, Allergan purchased an option right directly from LTI shareholders to acquire the company following completion of its Phase I trial There was no indication of value of the potential purchase.

LTI-291 aims to stimulate the activity of glucocerebrosidase (GCase) in the brain. In several lysosomal storage diseases, the activity of GCase is reduced due to a genetic mutation, and it is hoped that activation of the enzyme will ameliorate disease progression in these patients.

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