Amgen and Cytokinetics expand omecamtiv mecarbil accord

12 June 2013

USA-based Amgen (Nasdaq: AMGN), the world’s largest independent biotech company, has expanded its strategic collaboration with Cytokinetics (Nasdaq: CYTK) to include Japan. In 2006, Cytokinetics and Amgen entered into a collaboration to discover, develop and commercialize novel small-molecule therapeutics that activate cardiac muscle contractility for potential applications in the treatment of heart failure.

Omecamtiv mecarbil is the most advanced drug candidate in this collaboration. Initially, Cytokinetics` license to Amgen for omecamtiv mecarbil excluded Japan. Under the amendment to the collaboration announced today, the companies have agreed on terms expanding Amgen`s license for omecamtiv mecarbil and related compounds to include Japan.

Cytokinetics to get $25 million plus potential milestone payments and royalties

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