AstraZeneca expands billion dollar collaboration with Bicycle Therapeutics
Cambridge, UK-based biotech firm Bicycle Therapeutics is to expand its collaboration with AstraZeneca (LSE: AZN), to include additional targets in respiratory and cardio-metabolic diseases.
In 2016 the firms agreed a deal, worth up to $1 billion, to identify and develop bicyclic peptides in these therapy areas, based around Bicycle’s proprietary bicyclic peptide platform.
The firm is developing targeted cytotoxics (bicycle toxin conjugates), targeted innate immune activators and T-cell modulators for cancers of high unmet medical need.
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