Crescendo Biologics hits second target in Takeda collaboration

16 August 2018
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Imperial Innovations Group (AIM: IVO) portfolio company Crescendo Biologics says that it has achieved another technical milestone in its collaboration with a Japanese pharma major.

The development comes as part of the developer of targeted T-cell engagers’ global, strategic, multi-target collaboration and license agreement with Takeda Pharmaceutical (TYO: 4502) announced in October 2016, and provided for Crescendo to earn as much as $790 million in upfront and clinical development, regulatory and sales-based milestones

Under this agreement, UK-based Crescendo’s proprietary transgenic platform and engineering expertise is used to identify and configure Humabody-based therapeutics against certain targets selected by Takeda. Humabodies are a fraction of the size of antibodies and can be linked together in a “daisy chain” to fight tumors in more than one way.

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