Crystalys launches with $205M Series A financing

1 October 2025

San Diego, USA-based biotech start-up Crystalys Therapeutics has launched with a $205 million Series A financing to support its mission of addressing the significant unmet medical needs of people living with gout.

The financing was spearheaded by notable investment groups including Novo Holdings, SR One, and Catalys Pacific, with a consortium of other investors joining in support.

The financing round will support the advancement of global Phase III clinical studies evaluating the company's lead asset, dotinurad, a next-generation, once daily oral, URAT1 inhibitor with potential best-in-class safety and efficacy for the treatment of gout. Dotinurad has already demonstrated robust efficacy and a well-defined safety profile across multiple clinical studies, supporting its approval in Japan, China, Philippines and Thailand.

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