ESMO 2025: AstraZeneca shows off Imfinzi’s early-stage potential

17 October 2025

Anglo-Swedish pharma major AstraZeneca (LSE: AZN) has presented new data showing the impact of its PD-L1 inhibitor Imfinzi (durvalumab) in early cancer settings at the ongoing ESMO Annual Meeting.

One data presentation showed that adding one year of Imfinzi treatment to Bacillus Calmette-Guérin (BCG) induction and maintenance therapy delivered an early and sustained disease-free survival (DFS) benefit versus BCG alone.

This statistically-significant and clinically-meaningful improvement in DFS was seen in patients with BCG-naïve, high-risk non-muscle-invasive bladder cancer (NMIBC) compared to BCG treatment alone.

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