Ivonescimab ‘further establishes international leadership in cancer therapeutics’

27 August 2025

Chinese biopharma Akeso (HK: 9926) has presented the final analysis of the Phase III HARMONi-A lung cancer study of ivonescimab, demonstrating a statistically significant overall survival (OS) benefit and affirming its value across multiple endpoints, including progression-free survival (PFS) and OS. 

According to Akeso’s updates on the drug—presented alongside the company’s interim financial results for the past six months—ivonescimab has now demonstrated the potential to reshape the global treatment landscape across eight lung cancer and five other major tumor indications. It has already won approval in two non-small cell lung cancer indications in China over the past 18 months.

Consistently demonstrated superior efficacy compared to current immuno-oncology 1.0 therapies

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