Merus and Halozyme link up on petosemtamab development

17 November 2025

Dutch clinical-stage cancer drug developer Merus (Nasdaq: MRUS), which is developing innovative, full-length multi-specific antibodies and antibody drug conjugates (Biclonics, Triclonics and ADClonics), and USA-based Halozyme Therapeutics (Nasdaq: HALO) today announced they have entered into a global non-exclusive collaboration and license agreement.

Under the collaboration, Merus has licensed Halozyme's ENHANZE drug delivery technology, for the development and potential commercialization of subcutaneous administration of petosemtamab, an EGFR x LGR5 bispecific antibody.

Merus has recently agreed to be acquired by Denmark’s Genmab (Nasdaq: GMAB), in a deal worth up to $8 billion and expected to complete in the first quarter of 2026.

This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Try before you buy

Free

7 day trial access

Take a Free Trial

All the news that moves the needle in pharma and biotech
Exclusive features, podcasts, interviews, data analyses and commentary from our global network of life sciences reporters.
Receive The Pharma Letter daily news bulletin, free forever.

Become a subscriber

£820

Or £77 per month

Subscribe Now

Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
Daily roundup of key events in pharma and biotech.
Monthly in-depth briefings on Boardroom appointments and M&A news.
Choose from a cost-effective annual package or a flexible monthly subscription

The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK