New data support Tecentriq triplet in lung cancer

27 March 2018

An interim analysis shows that Roche’s (ROG: SIX) Phase III IMpower150 study has met its co-primary endpoint of overall survival (OS).

The trial is exploring a combination of Tecentriq (atezolizumab) and Avastin (bevacizumab) plus chemo to treat non-squamous non-small cell lung cancer (NSCLC) in the first-line setting.

The triple combo, which is being compared with Avastin and chemo alone, showed a survival benefit across key subgroups, including those with varying levels of PD-L1 expression. No new safety signals were detected.

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