New gene therapy could provide two-eye option for wet AMD

22 October 2024

Regenxbio (Nasdaq: RGNX) and AbbVie (NYSE: ABBV) have announced encouraging Phase II data for their partnered gene therapy, ABBV-RGX-314, at the American Academy of Ophthalmology meeting.

The study focused on patients with bilateral wet age-related macular degeneration (AMD), a condition that leads to vision loss and requires frequent treatment with current therapies.

The sub-study, involving nine patients, showed a 97% reduction in the need for anti-VEGF injections nine months after receiving ABBV-RGX-314. 78% of patients were able to go completely injection-free.

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