NICE endorses Spevigo for GPP

18 June 2025

The UK’s National Institute for Health and Care Excellence (NICE) has today recommended Spevigo (spesolimab) for the treatment of generalized pustular psoriasis (GPP) flares in adults in England and Wales.

Spevigo is marketed by German family-owned pharma major Boehringer Ingelheim, but the company has not released any sales figures publicly.

The drug has a UK list price of £15,000 ($20,415 ex-VAT) for a pair of 450mg vials, in guidance published in March.

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