Opdivo fails to best Nexavar in Phase III liver cancer test

24 June 2019

New Jersey, USA-based drugmaker Bristol-Myers Squibb (NYSE: BMY) has announced a Phase III trial miss for Opdivo (nivolumab), with top-line data showing the study did not meet its primary endpoint of overall survival (OS).

The firm has been comparing the checkpoint inhibitor with Bayer’s (BAYN: DE) Nexavar (sorafenib tosylate) as a first-line treatment in people with unresectable hepatocellular carcinoma (HCC).

Bristol-Myers said that no new safety signals were observed with Opdivo in the CheckMate-459 study, and that the full results will be presented at an upcoming meeting.

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