Phase III trial miss shakes faith in Gilead's Trodelvy

31 May 2024

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Following negative top-line results from the Phase III TROPiCS-04 study, shares in Gilead Sciences (Nasdaq: GILD) have fallen 3% in after-hours trading.

The study is comparing the first-in-class Trop-2-directed antibody-drug conjugate (ADC) Trodelvy (sacituzumab govitecan-hziy) with chemotherapy, in people with advanced or metastatic bladder cancer.

People in the trial had already been treated with platinum-containing chemotherapy and a checkpoint blocker.

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