Sanofi and Teva make progress with duvakitug collab
Sanofi (Euronext: SAN) and Teva Pharmaceutical (NYSE: TASE) have announced that the Phase IIb RELIEVE UCCD study met its primary endpoints.
The trial tests duvakitug in patients with ulcerative colitis and Crohn’s disease. Duvakitug is a monoclonal antibody targeting TL1A, a protein linked to inflammation and fibrosis in patients with moderate-to-severe inflammatory bowel disease.
The trial results showed that 47.8% of ulcerative colitis patients on the high dose achieved clinical remission at week 14, compared to 20.5% on placebo. In Crohn’s disease, 47.8% of patients receiving the high dose experienced an endoscopic response versus 13.0% on placebo.
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