Skyhawk links up with Merck KGaA on neuro meds

19 August 2025

Privately-held US biotech Skyhawk Therapeutics has announced a strategic research collaboration with Germany’s Merck KGaA (MRK: DE) focused on the discovery of novel RNA-targeting small molecules in select neurological indications with high unmet medical need.

Skyhawk will use its proprietary SkySTAR (Skyhawk Small molecule Therapeutics for Alternative splicing of RNA) platform to identify small molecule candidates directed at specific RNA targets designated by Merck. The collaboration aims to expand the potential of RNA modulation in diseases where traditional approaches have proven challenging, leveraging Skyhawk's industry-leading capabilities in RNA splicing modulation and Merck expertise in drug development and commercialization.

Potential $2 billion deal

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