Stronger antibody responses from Vaxart’s second gen vaccine tech
USA-based biotech Vaxart (Nasdaq: VXRT) has reported positive top-line results from a Phase I trial comparing its second-generation oral pill norovirus vaccine constructs to its first-generation constructs.
Shares in the San Francisco firm closed 28% higher Wednesday, when the data were shared.
The results show that the second-generation norovirus constructs produce statistically significant increases in GI.1 and GII.4 norovirus blocking antibodies - 141% and 94%, respectively - compared with first-generation constructs, supporting potential for improved protection against infection.
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