The week in pharma: action, reaction and insight – week to September 15, 2023

17 September 2023

By Barbara Obstoj-Cardwell. Editor

Among last week’s notable news, US drug developer Crinetics Pharmaceuticals released surprisingly good Phase III clinical trial results for its paltusotine in acromegaly. Germany’s Immatics has entered into a collaboration with the USA’s Moderna to develop mRNA-based cancer therapies. US cell and gene based immune-oncology drug developer 2seventry bio last week announced it is cutting its work force by 40% as part of a cost-cutting restructuring, and that chief executive Nick Leschly is stepping down. Also of note, Alnylam received a positive US Food and Drug Administration (FDA) advisory committee vote for its ATTR-cardiomyopathy candidate Onpattro (patisiran).

Crinetics’ PATHFNDR-1 impressive Phase III data for paltusotine in acromegaly

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