Tiltbio secures $26 million to advance ovarian cancer drug into Phase II

14 May 2025

Finnish biotech Tilt Biotherapeutics has raised $26 million (22.6 million euros) in a series B round to move its lead cancer immunotherapy into mid-stage trials for ovarian cancer, and to fund additional early-stage studies in melanoma and other indications.

The funding will allow the Helsinki-based company to start a Phase II trial of its oncolytic virus candidate, TILT-123 (igrelimogene litadenorepvec), in women with platinum-resistant ovarian cancer. The virus is designed to be delivered intravenously alongside T cell–based immunotherapies or checkpoint inhibitors to improve response rates in hard-to-treat tumors.

Tiltbio’s latest round was backed by existing supporters, including the European Innovation Council Fund, Finnish Industry Investment, Stephen Industries Inc Oy and Lifeline Ventures, which also led a previous $24 million raise in 2023. The new investment brings the company’s total funding to more than $79 million to date.

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