Clinical trial results indicate advance in Dengue vaccine research by Sanofi Pasteur

12 September 2012

The Dengue Vaccine Initiative (DVI) has welcomed new clinical trial results that reveal progress in developing the first-ever dengue vaccine. In a publication in The Lancet, pharmaceutical company Sanofi Pasteur, a unit of French drug major Sanofi (Euronext: SAN), reported results from the first study conducted to evaluate the efficacy of any dengue vaccine candidate against clinical dengue disease in a population naturally exposed to dengue.

The Lancet published first efficacy results of Sanofi Pasteur's dengue vaccine candidate showing efficacy against 61.2% of dengue virus type 1, 81.9% against type 3 and 90% against type 4. However, the data also showed that the vaccine lacks protection against serotype 2 in the epidemiological context of Thailand.

Still much work to be done

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