Corvas Completes Ph Ia With NAPc2
- Corvas has completed a Phase Ia trial of its anticoagulant,recombinant NAPc2. When administered to healthy male volunteers at doses ranging from 0.3-5.0mcg/ kg, a dose-dependent anticoagulant effect was observed, coupled with a half-life of more than 50 hours. No safety or tolerability concerns were noted, says the company. The drug will now be tested in a Phase Ib trial in deep vein thrombosis.
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