Cytheris, a clinical-stage biopharmaceutical company focused on the R&D of new therapies for immune modulation, reported positive data from a multicenter Phase I/IIa study designed to investigate the safety of Interleukin-7 therapy in chronically HIV-1 infected patients whose CD4 T-cell counts remained low despite treatment with anti-retroviral-therapies.
After 48 weeks, patients treated at the higher dose level showed a median increase in CD4 and CD8 T cell counts of 75% and 58%, respectively, from baseline levels.
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