Cytopia begins dosing in glioblastoma trial
Australian biotechnology firm Cytopia has commenced dosing patients in a Phase Ib/II study of CYT997, its novel vascular-disrupting anticancer agent, to treat glioblastoma multiforme. The clinical study will investigate the activity of CYT997 in combination with two other marketed anticancer agents in around 30 patients. This trial follows the successful conclusion last year of the company's Phase I safety study for intravenous CYT997, in which a prolonged delay in tumor growth was observed in seven of the trial's 31 advanced cancer patients.
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