Data on withdrawn drugs was faked; says hospital

16 March 2009

Data from studies claiming to show drugs such as the withdrawn products Vioxx (rofecoxib) and Bextra (valdecoxib) may been fabricated, reports  the Wall Street Journal.

The Massachusetts, USA-based Baystate Medical Center claims its former  chief of acute pain Scott Reuben had faked results that were published  in anesthesiology journals between 1996 and 2008. The journal Anesthsia  & Analgesia has retracted 10 of Dr Reuben's studies and warned about 11  more. Another journal, Anesthesiology, has retracted three of the  articles.

The list of drugs involved in the studies under scrutiny includes:  Pfizer's Bextra (valdecoxib), Celebrex (celecoxib) and Lyrica  (pregabalin); Merck & Co's Vioxx; and Wyeth's Effexor (venlafaxine).

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