DxS to develop V600E B-RAF mutation test
DxS, a UK-based personalized medicine company, has signed a non-exclusive global licensing agreement with the Wellcome Trust to provide a research test for use in clinical trials to detect the presence of the V600E B-RAF mutation, which is found in melanomas, as well as lung and thyroid cancers.
The V600E B-RAF mutation was identified by scientists at the Wellcome Trust and can be found in around 36% to 40% of skin and thyroid cancers and up to 13% of cancers in the large intestine.
Researchers will use the test to determine a patient's cancer mutation status, which may predict how they respond to cancer therapies. If clinical trials are successful, this could lead to a companion diagnostic to predict response for novel cancer therapies for skin, thyroid and large intestine cancers. Financial details were not disclosed.
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