An outside review of data on ecallantide, Dyax's investigational hereditary angioedema drug, posted on the US Food and Drug Administration's web site states that late-stage study findings do not provide "consistent and substantial evidence to support efficacy."
Despite this note of caution, observers were mostly confident of the drug's approval and, on the day the document was released, February 2, shares in Cambridge, Massachusetts, USA-based Dyax increased 2.4% to $3.44 in afternoon trading.
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