EC OKs Isentress for treatment-experienced HIV-1 patients
Merck, Sharp & Dohme, the UK subsidiary of US drug major Merck & Co, says that the European Commission has approved Isentress (raltegravir) in combination with other antivirals for the treatment of HIV-1 infection. The decision is based on efficacy and safety data from two double-blind trials of the agent, an inhibitor of the viral integrase gene, in therapy-experienced patients. In these assessments, Isentress, in combination with optimized background treatment, significantly reduced viral load and increased CD4 cell counts.
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