Japanese drugmaker Eisai has licensed the domestic rights to develop and commercialize Gliadel Wafer (polifeprosan 20 with carmustine implant) to Nobelpharma. Financial terms of the deal were not disclosed.
The agent is the only US-approved chemotherapeutic implant for use during surgical procedures for malignant glioma. It has been cleared in 18 countries worldwide, primarily in North America, Europe, and Southeast Asia. The National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology refer to the use of carmustine wafers as part of the treatment strategy for the disease.
Malignant gliomas are difficult to treat. Eisai expects that the timely development of Gliadel Wafer by Nobelpharma, which is actively committed to progressing drugs for highly unmet medical needs that are strongly desired by patient advocacy groups or academic society.
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