Frankfurt, Germany-based Ergomed has signed an agreement with US biotechnology major Genzyme for the co-development of tasidotin, a novel dolastatin analogue that has shown efficacy in previous oncology trials.
As part of the deal, Ergomed will advance the oral formulation of tasidotin, developed by Genzyme, into clinical trials. In an earlier Phase II study, the intravenous formulation of the drug demonstrated clinical activity in patients with melanoma.
"Tasidotin has a promising future with established human clinical safety and a solid rationale for efficacy against particular cancers," said Ergomed chief executive Miroslav Reljanovic. "We are delighted to have signed our second development license agreement in line with our stated strategy for Ergomed's Product Development Division to assist both biotechnology and pharmaceutical partners in the successful clinical development of drug candidates," he added.
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