Updated study findings from the RECORD-1 study show that advanced kidney cancer patients on Novartis' RAD001 (everolimus) had no tumor growth for 4.9 months versus 1.9 months for those receiving placebo (p<0.001). In addition, after more than 10 months of treatment, 25% of subjects still had no tumor growth.
According to Bernard Escudier, head of Immunotherapy and Innovative Therapy Unit at the Gustave-Roussy Institute, Paris, France, the results, presented at the 33rd European Society for Medical Oncology Congress in Stockholm, Sweden, should become part of the treatment paradigm for this patient population.
Earlier this year, interim results from RECORD-1 were used to submit regulatory applications for RAD001 as a treatment for metastatic renal cell carcinoma, for which the agent was granted priority review by the US Food and Drug Administration.
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