ExonHit looking to partner novel AD drug

9 March 2009

French RNA specialist company ExonHit Therapeutics has completed patient  enrolment for its Phase IIa trial assessing its lead compound EHT 0202  in patients with Alzheimer's disease.

The multicenter, randomized, double-blind, placebo-controlled study  enrolled approximately 150 patients with mild-to-moderate AD. The effect  of either 40mg or 80mg of EHT 0202 as adjunctive therapy to an  acetylcholinesterase inhibitor will be evaluated in comparison to  placebo over a three-month period. Study results will be available in  the fourth quarter of 2009.

Loic Maurel, president of ExonHit, said: "our strategy is to bring EHT  0202 up to the end of the ongoing study and then to look for a partner  to move EHT 0202 through further clinical development. We have already  met with several pharmaceutical companies that are looking forward to  the Phase IIa results."

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