French RNA specialist company ExonHit Therapeutics has completed patient enrolment for its Phase IIa trial assessing its lead compound EHT 0202 in patients with Alzheimer's disease.
The multicenter, randomized, double-blind, placebo-controlled study enrolled approximately 150 patients with mild-to-moderate AD. The effect of either 40mg or 80mg of EHT 0202 as adjunctive therapy to an acetylcholinesterase inhibitor will be evaluated in comparison to placebo over a three-month period. Study results will be available in the fourth quarter of 2009.
Loic Maurel, president of ExonHit, said: "our strategy is to bring EHT 0202 up to the end of the ongoing study and then to look for a partner to move EHT 0202 through further clinical development. We have already met with several pharmaceutical companies that are looking forward to the Phase IIa results."
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