FDA investigating 30 reports of cancer in children taking TNF blockers
The US Food and Drug Administration is investigating the possible link between tumor necrosis factor blockers and the development of lymphoma and other cancers in children and young adults.
The US regulator is reviewing approximately 30 reports of cancer in under 18 year olds who were treated with TNF blockers for the juvenile idiopathic arthritis, Crohn's disease or other conditions.
The drugs under scrutiny include Johnson & Johnson's Remicade (infliximab), fellow US health care major Abbott's Humira (adalimumab), Belgian drugmaker UCB's Cimzia (certolizumab pegol) and US biotechnology giant Amgen and drugmaker Wyeth's Enbrel (etanercept).
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