Research briefs on Merck & Co's boceprevir and Bayer's Xarelto; legal updates from AstraZeneca and Daiichi Sankyo/Actavis

5 August 2010

US drug giant Merck & Co has reported results from two pivotal Phase III studies: HCV SPRINT-2 (n=1097) and HCV RESPOND-2 (n=403) of boceprevir, an oral hepatitis C protease inhibitor, for the treatment of chronic hepatitis C. In both the studies, data indicated that addition of boceprevir to treatment with Pegintron (peginterferon alfa-2b) and Rebetol (ribavirin, USP) (Peg/riba) significantly increased the percentage of patients who achieved sustained virologic response, compared to control groups who received Peginterferon/ribavirin plus placebo.

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