Glycomine’s $115 million Series C to advance lead candidate into Phase IIb trial

16 April 2025

Californian biotech Glycomine has raised $115 million in a Series C financing to advance its lead candidate, GLM101, into a Phase IIb trial.

GLM101, a first-in-class mannose-1-phosphate replacement therapy, is in development for phosphomannomutase-2 congenital disorder of glycosylaNon (PMM2-CDG), a rare and life- threatening genetic disorder with no approved treatments. 

Glycomine has enrolled more than 20 participants across Europe and the USA in its ongoing Phase II study, and recently started dosing in pediatric patients.

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