GSK forms amyloidosis partnership with Univ

29 March 2009

UK drug major GlaxoSmithKline has formed a collaboration to develop a drug-antibody dual treatment for amyloidosis with the University College  London spinout company Pentraxin Therapeutics.

Under the terms of the agreement, Pentraxin will receive undisclosed,  early-stage, success-based and development milestones, as well as  royalties.

The partnership will focus on the small-molecule drug CHPHC, which has  shown early results, but could not achieve a significant benefit for  patients with advanced disease. Pentraxin achieved greater success by  combining CPHPC treatment with an antibody that seeks out the amyloid  deposits in the organs of mice.

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