ICER evidence report on Vertex new treatment for acute pain

6 February 2025

US health technology assessor the Institute for Clinical and Economic Review (ICER) yesterday posted its revised Evidence Report assessing the comparative clinical effectiveness and value of suzetrigine, from Vertex Pharmaceuticals (Nasdaq: VRTX), for the treatment of acute pain.

Under the trade name Journavx, suzetrigine –an oral, non-opioid, highly selective NaV1.8 pain signal inhibitor - was granted approval by the US Food and Drug Administration for the treatment of adults with moderate-to-severe acute pain.

Leerink Partners analysts have previously forecast 2032E Vertex NaV1.8 neuropathic pain sales of $7.0 billion to $5.3 billion. VisibleAlpha consensus estimate is $3.4 billion.

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