Innovent’s Sycume to transform thyroid eye disease landscape in Asia
Innovent Biologics (HKEX: 01801) has recently received approval for Sycume (teprotumumab biosimilar) to treat thyroid eye disease (TED) in China, making it the country’s first insulin-like growth factor 1 receptor (IGF-1R) monoclonal antibody cleared for TED by the National Medical Products Administration (NMPA).
It represents a significant breakthrough and has the potential to transform the standard of care for TED patients in China and Asia, says pharma analytics company GlobalData.
The globally approved anti-IGF-1R Tepezza (teprotumumab-trbw, from Amgen (Nasdaq: SMGN) and Horizon Therapeutics) is not available in China and is reported to have an extremely high cost (over $17,000 per course of treatment in the US). Innovent, on the other hand, has a competitive edge owing to Sycume’s liquid injection formulation, which offers strengths in terms of stability, cost, simplicity of the manufacturing process, and patient compliance.
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