J&J presents long-term Opsynvi findings at ATS
US healthcare giant Johnson & Johnson (NYSE: JNJ) presented long-term findings from the 24-month open-label extension of the A DUE trial of Opsynvi (macitentan and tadalafil) in pulmonary arterial hypertension (PAH) during a late-breaking oral session at the American Thoracic Society (ATS) Conference.
In the final analysis of the open-label period of the A DUE study, investigators evaluated the long-term effects of a macitentan and tadalafil fixed-dose combination (M/T FDC) on overall survival, exercise capacity, reduction of cardiac biomarker N-terminal pro-B-type natriuretic peptide (NT-proBNP), hospitalizations, and safety/tolerability.
Key findings from the open-label period include:
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