The creation of Japan's Kyowa Hakko Kirin, through the merger of Kyowa Hakko and Kirin Pharma (Marketletter October 29, 2007), may harm competition in the country's granulocyte-colony stimulating factor market, according to the nation's Fair Trade Commission. The firm has been in talks with the FTC since the merger and is proposing to sell its NEU-UP (nartograstim), for the treatment of neutropenia resulting from cancer chemotherapy, to recover its pre-merger status. The only other G-CSF drugs on the Japanese market are KHK's own Gran (fligrastim) and Chugai's Neutrogin (lenograstim).
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