J&J’s Tecvayli now recommended as fourth-line myeloma option

10 October 2024

US healthcare giant Johnson & Johnson’s (NYSE: JNJ) Tecvayli (teclistamab) has been recommended by the National Institute for Health and Care Excellence (NICE) as a first-line option to treat myeloma in England and Wales.

The bispecific B-cell maturation antigen-directed CD3 T-cell engager will be given to those who have had at least three treatments for the disease.

These three treatments must have included an immunomodulatory drug, a proteasome inhibitor and an anti-CD38 antibody. The patients’ cancer also must have progressed since their last treatment.

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