Lilly compound shows insulinotropic effect
US drug major Eli Lilly presented positive Phase II results for LY2189265, its investigational glucagon-like peptide-1 analog administered subcutaneously once-weekly for the treatment of type 2 diabetes at the American Diabetes Association's annual scientific sessions in New Orleans.
In the Phase II study, known as GBCJ, LY2189265 was significantly superior to placebo in reducing key measures of glycemic control, including fasting serum glucose and hemoglobin A1C. The agent also showed an insulinotropic effect, suggesting it produced the desired outcome in participants.
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