Long-term weight loss with DSM's Fabuless

A recent clinical trial suggests that daily consumption of yogurt containing Dutch firm DSM's satiety ingredient Fabuless significantly aids weight maintenance after weight loss. The placebo-controlled, double-blind test aimed to investigate the long-term effects of the agent on a group of women aged 18-55 and the results, which appeared in the Journal of Obesity, show that it successfully reduces appetite and weight gain after dieting.

Fabuless is a patent-protected combination of naturally-occurring oat and palm oils formulated in a novel emulsion. The microstructure of Fabuless is thought to prevent the digestion of palm oil droplets until relatively deep in the small intestine. Undigested fat arriving in the latter part of the small intestine triggers a satiety signal. Because they feel no need to take in more calories, consumers can eat less but still feel satisfied, DSM noted.

In the study, conducted by researchers at the Netherlands' University of Maastricht, 50 overweight females underwent a six-week weight loss period, followed by 18 weeks weight maintenance. During the weight maintenance phase, they consumed yogurt containing either Fabuless or placebo. Those who consumed Fabuless showed no significant regain in body weight after six weeks of dieting. This was in contrast to the placebo group, which experienced significant weight gain.