Medarex in up to $225M C. diff deal with Merck & Co

21 April 2009

Merck & Co and fellow USA-based firm Medarex have licensed an investigational, fully-human monoclonal antibody combination developed  to target and neutralize Clostridium difficile toxins A and B from the  Massachusetts Biologic Laboratories.

Under the terms of the agreement, Merck gains worldwide rights to  develop and commercialize CDA-1 and CDB-1 (also known as  MDX-066/MDX-1388 and MBL-CDA1/MBL-CDB1). Medarex and MBL will receive an  upfront payment of $60.0 million and are potentially eligible for  additional cash payments up to $165.0 million on the achievement of  certain milestones associated with the development and approval of a  drug candidate, as well as double-digit royalties. All payments will be  divided equally.

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