Medarex partner initiates lupus Ab study
US biopharmaceutical company Medarex says that its partner MedImmune, recently bought by Anglo-Swedish drugmaker AstraZeneca (Marketletter April 30), has initiated a Phase Ib trial of the developmental therapeutic antibody MEDI-545 in the treatment of lupus erythematosus.
The antibody, which was generated using Medarex' UltiMAb Human Antibody Development System, is also being evaluated in a Phase I dose-escalation trial as a therapy for psoriasis.
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