Merck & Co/Schering-Plough's combo statin disappoints in ENHANCE trial
US drug majors Schering-Plough and Merck & Co have reported disappointing data from the ENHANCE trial of their co-developmental cholesterol-lowering drug candidate Vytorin (ezetimibe and high-dose simvastatin) versus simvastatin alone.
The news - which had been awaited by the investment community - showed that that the combination drug had failed to produce the desired effects and saw S-P's share price fall 3% to $27.02 while Merck's declined 2% to $59.40 in early trading on Janury 14, when the study results were revealed.
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