Merck KGaA shares rise 4% as Erbitux meets Ph III endpoint in mCRC
German drugmaker Merck KGaA's Erbitux (cetuximab) plus irinotecan-based therapy met the primary endpoint of increasing median duration of progression-free survival in patients with previously-untreated metastatic colorectal cancer in a Phase III study. In morning trading on the day of the announcement, January 10, the firm's share price rose 3.8% to 9.50 euros. The randomized Phase III international CRYSTAL trial evaluated over 1,000 patients treated with Erbitux plus FOLFIRI (irinotecan-based chemotherapy) versus those on FOLFIRI alone.
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