MHRA nod for Hympavzi for hemophilia A or B

22 April 2025

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has approved Hympavzi (marstacimab) to prevent or reduce bleeding in patients 12 years of age and older weighing at least 35kg with hemophilia A and B.

Developed by US pharma giant Pfizer (NYSE: PFE), this medicine is the first of its kind to work by targeting a protein in the blood clotting process, noted the MHRA. The drug was approved by the European Commission and the US Food and Drug Administration (FDA) late last year.
Hemophilia A and B are inherited bleeding disorders caused by a lack of factor VIII (haemophilia A) or factor IX (hemophilia B) which are proteins required for blood to clot and to stop bleeding.

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