Merck Sharp & Dohme's angiotensin II receptor antagonist Cozaar(losartan) has been introdued in a new 100mg formulation in the UK. The new dose is designed to make it easier for physicians and patients to address the results of the RENAAL trial, which showed that Cozaar 100mg reduced the risk of end-stage renal disease or death by 28% in hypertensive patients with type 2 diabetes and renal disease (Marketletter June 4, 2001).
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